What we do

The Roy Lab studies how the retina processes visual information and how this process is disrupted in glaucoma. We use a cross-species framework, along with genetic, electrophysiological, imaging, and computational approaches to dissect the cellular and molecular mechanisms underlying visual signaling in healthy and diseased conditions. We partner with researchers and clinicians to design and test strategies for vision restoration. 

  • Glaucoma is a neurodegenerative disease that causes irreversible blindness in millions of people worldwide. Ocular hypertension is the leading risk factor for glaucoma. We aim to understand the mechanisms by which ocular hypertension disrupts signaling in retinal cells and in axons of the optic nerve, and how these changes alter vision. Using preclinical animal models in a cross-species framework, we investigate disease mechanisms at the cellular level. We hope to that these studies will guide development of more effective, targeted neuroprotective therapies that prevent vision loss.

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  • How do cell types and their connectivity in the retina support feature detection? How does this architecture vary across taxa - from rodents to humans?

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  • Maybe you want to turn a hobby into something more

    It all begins with an idea. Maybe you want to launch a business. Maybe you want to turn a hobby into something more. Or maybe you have a creative project to share with the world. Whatever it is, the way you tell your story online can make all the difference.

    Make It

  • Maybe you have a creative project to share with the world

    It all begins with an idea. Maybe you want to launch a business. Maybe you want to turn a hobby into something more. Or maybe you have a creative project to share with the world. Whatever it is, the way you tell your story online can make all the difference.

    Make It

Lab philosophy

We study the retina

We love bold ideas

We welcome creative minds

We make discovery a team sport